Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728938 | 0.91 | AKR1B1 (0.50) | AKR1B1AKR1B10AKR1A1CHRM5 | |
| SCHEMBL9729042 | 0.91 | AKR1B1 (0.50) | AKR1B1AKR1B10AKR1A1CHRM5 | |
| SCHEMBL8319660 | 0.88 | AKR1B1 (0.54) | AKR1B1AKR1B10AKR1A1CHRM5 | |
| SCHEMBL8805167 | 0.87 | AKR1B1 (0.53) | AKR1B1AKR1B10AKR1A1CHRM5 | |
| SCHEMBL8319413 | 0.85 | AKR1B1 (0.51) | AKR1B1AKR1B10AKR1A1CHRM5 | |
| SCHEMBL8805641 | 0.83 | AKR1B1 (0.52) | AKR1B1AKR1B10AKR1A1CHRM5 | |
| SCHEMBL9871300 | 0.81 | AKR1B1 (0.52) | AKR1B1AKR1B10AKR1A1CHRM5 | |
| SCHEMBL9728713 | 0.80 | AKR1B1 (0.46) | AKR1B1AKR1B10AKR1A1CHRM5 | |
| SCHEMBL8322894 | 0.78 | AKR1B1 (0.54) | AKR1B1AKR1B10AKR1A1 | |
| SCHEMBL8805046 | 0.78 | AKR1B1 (0.54) | AKR1B1AKR1B10AKR1A1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081241-A | Diabetes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |