Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAN2A1 | Q16706 | 2/20 | 0.39 |
| ▸ | MAN1B1 | Q9UKM7 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | MC4R | P32245 | 3/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729326 | 0.82 | AOC3 (0.57) | AOC3TSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9728971 | 0.78 | AOC3 (0.52) | AOC3TSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29433956 | 0.76 | AOC3 (0.53) | AOC3TSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9729467 | 0.76 | AOC3 (0.53) | AOC3TSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL24322415 | 0.73 | MAPT (0.56) | TSHRNPY1RNPY2RPLK1POLB | |
| SCHEMBL11713374 | 0.73 | TSHR (0.49) | AOC3TSHRNPY1RNPY2RPLK1 | |
| SCHEMBL4083083 | 0.73 | AOC3 (0.53) | AOC3TSHRSLC6A4MAN2A1MAN1B1 | |
| SCHEMBL9729722 | 0.72 | AOC3 (0.49) | AOC3TSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5417971 | 0.70 | AOC3 (0.60) | AOC3TSHRNPY1RNPY2RMC4R | |
| Hydrochloric Acid SCHEMBL9737723 | 0.69 | AOC3 (0.58) | AOC3TSHRNPY1RNPY2RSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171753-A | Derivatives of 2-amino-1-phenylethanol having antiulcer activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-12-15 | — | — | US | disclosed |