Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 8/20 | 0.80 |
| ▸ | PIM1 | P11309 | 8/20 | 0.80 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3165082 | 0.84 | NTRK1 (0.76) | NTRK1PIM1ACVR1L3MBTL1GAA | |
| SCHEMBL29283642 | 0.82 | NTRK1 (0.81) | NTRK1PIM1ACVR1L3MBTL1GAA | |
| SCHEMBL11472391 | 0.76 | NTRK1 (0.68) | NTRK1PIM1ACVR1KMT2AMEN1 | |
| SCHEMBL9728518 | 0.74 | NTRK1 (0.70) | NTRK1PIM1ACVR1L3MBTL1KMT2A | |
| SCHEMBL31278133 | 0.71 | NTRK1 (0.59) | NTRK1PIM1ACVR1KMT2AMEN1 | |
| SCHEMBL11469306 | 0.71 | MEN1 (0.77) | NTRK1PIM1ACVR1GAAKMT2A | |
| SCHEMBL2107212 | 0.71 | NTRK1 (0.60) | NTRK1PIM1ACVR1L3MBTL1GAA | |
| SCHEMBL2108181 | 0.71 | NTRK1 (0.57) | NTRK1PIM1ACVR1KMT2AMEN1 | |
| SCHEMBL11346886 | 0.71 | KDM4E (0.78) | NTRK1PIM1ACVR1L3MBTL1GAA | |
| SCHEMBL3161949 | 0.68 | MEN1 (0.60) | NTRK1PIM1ACVR1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169850-A | Neurotropic or hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| US-5059691-A | Anxiolytic agents; hypotensive agents; nervous system disorders; cognition activators | AMERICAN CYANAMID COMPANY (US) | 1991-10-22 | — | — | US | disclosed |