Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329933 | 0.77 | KDM4E (0.61) | KDM4EL3MBTL1 | |
| SCHEMBL6893033 | 0.77 | HPGD (0.50) | HPGDPKMCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3353372 | 0.77 | HPGD (0.50) | HPGDPKMCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22044302 | 0.76 | ANPEP (0.59) | HPGDPKMKDM4ETDP1ALDH1A1 | |
| SCHEMBL15662928 | 0.76 | HPGD (0.66) | HPGDKDM4ETDP1ALDH1A1KMT2A | |
| SCHEMBL9729131 | 0.76 | HPGD (0.55) | HPGDPKMCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23531478 | 0.74 | KMT2A (0.70) | HPGDPKML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL18541807 | 0.74 | KMT2A (0.70) | HPGDPKML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL28130536 | 0.74 | KMT2A (0.70) | HPGDPKML3MBTL1ALDH1A1KMT2A | |
| SCHEMBL5431141 | 0.73 | KDM4E (0.50) | HPGDPKMCYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803200-A | SHIPPING FEVER SYNDROME | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-02-07 | — | — | US | claimed |
| US-5171753-A | Derivatives of 2-amino-1-phenylethanol having antiulcer activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-12-15 | — | — | US | disclosed |
| US-4803200-A | SHIPPING FEVER SYNDROME | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-02-07 | — | — | US | disclosed |