Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 3/20 | 0.38 |
| ▸ | FNTB | P49356 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9730940 | 0.99 | TACR1 (0.56) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9373109 | 0.87 | TACR1 (0.68) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9272085 | 0.87 | TACR1 (0.68) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730542 | 0.85 | TACR1 (0.59) | TACR1MEN1CYP3A4MAPTTSHR | |
| Hydrochloric Acid SCHEMBL9730405 | 0.84 | TACR1 (0.58) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730357 | 0.81 | TACR1 (0.54) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729135 | 0.80 | TACR1 (0.55) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729686 | 0.79 | TACR1 (0.58) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730090 | 0.77 | TACR1 (0.56) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729277 | 0.77 | TACR1 (0.36) | TACR1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112988-A | ISOINDOLONE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-05-12 | — | — | US | disclosed |