Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81650 | 0.69 | NISCH (0.59) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL1467709 | 0.68 | KDM4E (0.31) | KDM4E | |
| SCHEMBL409012 | 0.68 | NISCH (0.44) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL28425230 | 0.67 | NISCH (0.56) | NISCHMTORADKALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL1536214 | 0.67 | NISCH (0.56) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL28581729 | 0.67 | NISCH (0.52) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL30216772 | 0.67 | NISCH (0.52) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL5491437 | 0.67 | — | — | |
| SCHEMBL24575957 | 0.67 | NISCH (0.42) | NISCHMTORADKALDH1A1MEN1 | |
| SCHEMBL4405939 | 0.67 | NISCH (0.42) | NISCHMTORADKALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2781512-B1 | OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | UNIV SHANGHAI JIAOTONG (CN) | 2017-06-28 | — | — | EP | claimed |
| WO-2015173321-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A PARTICULAR IMIDAZOLE COUPLER AND AN OXIDATION BASE | L'OREAL (FR) | 2015-11-19 | — | — | WO | claimed |
| WO-2015173321-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A PARTICULAR IMIDAZOLE COUPLER AND AN OXIDATION BASE | L'OREAL (FR) | 2015-11-19 | — | — | WO | disclosed |
| US-20110021505-A1 | Use of sulfonyl-substituted 2-sulfonylaminobenzoic acid N-phenylamides in the treatment of pain | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-01-27 | — | — | US | disclosed |
| CN-101898977-A | GABA (Gamma-Aminobutyric Acid) conjugates and using method thereof | FENG XU | 2010-12-01 | — | — | CN | disclosed |
| CN-101898978-A | Eflornithine prodrug and conjugate and using method thereof | FENG XU | 2010-12-01 | — | — | CN | disclosed |
| EP-0984962-A1 | SUBSTITUTED 4-BENZOYL-PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998050379-A1 | SUBSTITUTED 4-BENZOYL-PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-12 | — | — | WO | disclosed |
| US-5554632-A | CENTRAL NERVOUS SYSTEM | NEUROSEARCH A/S (DK) | 1996-09-10 | — | — | US | disclosed |
| US-5410052-A | Useful for extraction of ligand such as molecular oxygen from fluid environment and for release of such ligand | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-25 | — | — | US | disclosed |
| US-4959135-A | OXYGEN | AQUANAUTICS CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |
| WO-1988006641-A1 | POLYALKYLAMINE COMPLEXES FOR LIGAND EXTRACTION AND GENERATION | AQUANAUTICS CORPORATION (US) | 1988-09-07 | — | — | WO | disclosed |
| US-4014874-A | Process for the manufacture of 3-substituted thiomethyl-7-amino-2-cephem-4-carboxylic acid compound | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021505-A1 | Use of sulfonyl-substituted 2-sulfonylaminobenzoic acid N-phenylamides in the treatment of pain | SCN1A, SCN2A, CACNA1A | NISCH 279/4885MTOR 3440/4885ADK 3317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.