Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581513 | 0.90 | AR (0.44) | ARALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL18244728 | 0.88 | AR (0.46) | AR | |
| SCHEMBL30054555 | 0.88 | AR (0.46) | AR | |
| SCHEMBL10670312 | 0.86 | PTPN5 (0.37) | ARALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL9581295 | 0.86 | AR (0.35) | ARALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL9465161 | 0.79 | AR (0.42) | ARALDH1A1CYP3A4KDM4ECYP11B1 | |
| SCHEMBL31195171 | 0.79 | AR (0.42) | ARALDH1A1CYP3A4KDM4ECYP11B1 | |
| SCHEMBL8431056 | 0.79 | CYP3A4 (0.70) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL25983230 | 0.79 | AR (0.40) | ARKIF11CES2CYP11B1CYP11B2 | |
| SCHEMBL23503139 | 0.78 | AR (0.40) | ARTSHRKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5109004-A | Cyano phenyl-substituted with heterocylic compound; insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0398499-A2 | Insecticides | ZENECA LIMITED (GB) | 1990-11-22 | — | — | EP | disclosed |
| CN-1046526-A | New compound and preparation method thereof | ICI PLC (GB) | 1990-10-31 | — | — | CN | disclosed |