Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.67 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670960 | 0.84 | NAPRT (0.63) | NAPRTDAOKDM4EGAAMAPT | |
| SCHEMBL1315187 | 0.81 | NAPRT (0.59) | NAPRTDAOKDM4EGAAMAPT | |
| SCHEMBL440492 | 0.80 | NAPRT (1.00) | NAPRTDAOKDM4EGAAMAPT | |
| Hydrochloric Acid SCHEMBL17597625 | 0.78 | NAPRT (0.96) | NAPRTDAOKDM4EGAAMAPT | |
| Hydrochloric Acid SCHEMBL14741024 | 0.78 | NAPRT (0.96) | NAPRTDAOKDM4EGAAMAPT | |
| SCHEMBL425117 | 0.77 | NAPRT (0.72) | NAPRTDAOKDM4EGAAMAPT | |
| SCHEMBL8193694 | 0.77 | NAPRT (0.72) | NAPRTDAOKDM4EGAAMAPT | |
| SCHEMBL8077362 | 0.74 | NAPRT (0.67) | NAPRTDAOKDM4EGAAMAPT | |
| SCHEMBL3182033 | 0.74 | NAPRT (0.67) | NAPRTDAOKDM4EGAAMAPT | |
| SCHEMBL2281551 | 0.74 | NAPRT (0.67) | NAPRTDAOKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4230366-A | — | — | None | — | — | JP | disclosed |
| JP-H04230366-A | NICOTINIC ACID DERIVATIVES | BAYER AG | 1992-08-19 | — | — | JP | disclosed |