Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.50 |
| ▸ | KDM1B | Q8NB78 | 7/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731123 | 0.79 | KDM1A (0.50) | KDM1AKDM1BKCNH2CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL9731435 | 0.78 | KDM1A (0.57) | KDM1AKDM1BKCNH2CHRNB2CHRNB4 | |
| SCHEMBL23250453 | 0.75 | KDM1A (0.47) | KDM1AKDM1BKCNH2CHRNB2CHRNB4 | |
| SCHEMBL31424337 | 0.75 | KDM1A (0.47) | KDM1AKDM1BKCNH2CHRNB2CHRNB4 | |
| SCHEMBL9731784 | 0.74 | KDM1A (0.49) | KDM1AKDM1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9731708 | 0.70 | KDM1A (0.41) | KDM1AKDM1BKCNH2 | |
| SCHEMBL9731852 | 0.68 | KDM1A (0.45) | KDM1AKDM1BKCNH2IDO1 | |
| SCHEMBL9731242 | 0.68 | TSHR (0.39) | KDM1AKDM1BKCNH2IDO1 | |
| SCHEMBL27447794 | 0.67 | KDM1A (0.43) | KDM1AKDM1BKCNH2CHRNB2CHRNB4 | |
| SCHEMBL4568233 | 0.67 | KDM1A (0.43) | KDM1AKDM1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091429-A | Antidepressant and analgesic with side effects reduction | LABORATOIRES LUCIEN (FR) | 1992-02-25 | — | — | US | disclosed |
| US-5081254-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4929613-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0306764-A2 | 4-Quinolone-3-carboxylic-acid derivatives and their use as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-03-15 | — | — | EP | disclosed |