(S)-2-Aminoadipic Acid

(S)-2-Aminoadipic Acid

SCHEMBL97323

N[C@@H](CCCC(=O)O)C(=O)O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.73
GRM8 O00222 2/20 0.73
GRM6 O15303 2/20 0.73
GRM7 Q14831 2/20 0.73
GRM4 Q14833 2/20 0.73
GRIN2D O15399 1/20 0.73
GRIN3B O60391 1/20 0.73
CYP1A2 P05177 1/20 0.73
GRIK1 P39086 1/20 0.73
GRM5 P41594 1/20 0.73
GRIA1 P42261 1/20 0.73
GRIA2 P42262 1/20 0.73
GRIA3 P42263 1/20 0.73
SLC1A3 P43003 1/20 0.73
SLC1A2 P43004 1/20 0.73
SLC1A1 P43005 1/20 0.73
GRIA4 P48058 1/20 0.73
GRIN1 Q05586 1/20 0.73
GRIN2A Q12879 1/20 0.73
GRIK2 Q13002 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(S)-2-Aminoadipic Acid SCHEMBL41328 1.00 GSR (0.73) GSRGRM8GRM6GRM7GRM4
(S)-2-Aminoadipic Acid SCHEMBL561980 1.00 GSR (0.73) GSRGRM8GRM6GRM7GRM4
(S)-2-Aminoadipic Acid SCHEMBL2022365 1.00 GSR (0.73) GSRGRM8GRM6GRM7GRM4
(S)-2-Aminoadipic Acid SCHEMBL8583999 0.98 GSR (0.70) GSRGRM8GRM6GRM7GRM4
(S)-2-Aminoadipic Acid SCHEMBL21494658 0.98 GSR (0.70) GSRGRM8GRM6GRM7GRM4
(S)-2-Aminoadipic Acid SCHEMBL4715811 0.98 GSR (0.70) GSRGRM8GRM6GRM7GRM4
(S)-2-Aminoadipic Acid SCHEMBL318309 0.98 GSR (0.70) GSRGRM8GRM6GRM7GRM4
(S)-2-Aminoadipic Acid SCHEMBL21494655 0.98 GSR (0.70) GSRGRM8GRM6GRM7GRM4
(S)-2-Aminoadipic Acid SCHEMBL28692494 0.98 GSR (0.70) GSRGRM8GRM6GRM7GRM4
(S)-2-Aminoadipic Acid SCHEMBL29507356 0.98 GSR (0.70) GSRGRM8GRM6GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2888 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117603532-B Ultrahigh aging-resistant polypropylene composite material and preparation method and application thereof 万华化学集团股份有限公司 2026-05-22 CN claimed
CN-122071958-A Deep coal bed gas geological dessert description method 中国石油集团长城钻探工程有限公司 2026-05-22 CN claimed
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 CN claimed
US-12630588-B2 Bicyclic peptide ligands specific for CD137 BICYCLETX LIMITED (GB) 2026-05-19 US claimed
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN UNIV CALIFORNIA (US) 2026-05-07 US claimed
EP-4736946-A2 AMYLIN ANALOGUES Zealand Pharma A/S (DK) 2026-05-06 EP claimed
EP-4736945-A2 AMYLIN ANALOGUES Zealand Pharma A/S (DK) 2026-05-06 EP claimed
EP-4735021-A1 COMBINATION THERAPY Zealand Pharma A/S (DK) 2026-05-06 EP claimed
US-12616737-B2 Liquid formulations of amylin analogues ZEALAND PHARMA A/S (DK) 2026-05-05 US claimed
US-20260115256-A1 HUMAN AMYLIN ANALOG, AND DERIVATIVE THEREOF AND USE THEREOF HANGZHOU SCIWIND BIOSCIENCES CO., LTD. (CN) 2026-04-30 US claimed
WO-2012010851-A1 CAPILLARY ELECTROPHORESIS OF CARBOHYDRATES CAMBRIDGE ENTERPRISE LIMITED (GB) 2012-01-26 WO claimed
CN-102174632-A Bio-catalytic deracemization preparation method of non-natural L-amino acid UNIV CHONGQING POSTS & TELECOM 2011-09-07 CN claimed
WO-2007098089-A2 TREATMENT OF HYPERPROLIFERATIVE DISEASES WITH METHOTREXATE N-OXIDE AND ANALOGS NOVACEA, INC. (US) 2007-08-30 WO claimed
US-20050118598-A1 Organic compounds GARCIA-ECHEVERRIA CARLOS (CH) 2005-06-02 US claimed
EP-1478665-A2 ORGANIC COMPOUNDS HAVING ANTI-ANGIOGENIC ACTIVITY Novartis AG (CH) 2004-11-24 EP claimed
EP-0819761-B1 PROCESS FOR PRODUCING L-2-AMINOADIPIC ACID MERCIAN CORP (JP) 2004-10-13 EP claimed
WO-2003070769-A2 ORGANIC COMPOUNDS HAVING ANTI-ANGIOGENIC ACTIVITY NOVARTIS AG (CH) 2003-08-28 WO claimed
US-20020035243-A1 Transport system conjugates PENTAPHARM AG (CH) 2002-03-21 US claimed
US-5906927-A Process for producing L-2-aminoadipic acid MERCIAN CORPORATION (JP) 1999-05-25 US claimed
EP-0819761-A1 PROCESS FOR PRODUCING L-2-AMINOADIPIC ACID MERCIAN CORPORATION (JP) 1998-01-21 EP claimed