⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748360 | 0.79 | — | — | |
| SCHEMBL3808280 | 0.73 | — | — | |
| SCHEMBL15921926 | 0.73 | — | — | |
| SCHEMBL11017060 | 0.71 | HIF1A (0.32) | — | |
| SCHEMBL19182945 | 0.71 | KDM4E (0.31) | — | |
| SCHEMBL2269276 | 0.70 | — | — | |
| SCHEMBL582879 | 0.70 | — | — | |
| SCHEMBL7749844 | 0.70 | TSHR (0.38) | — | |
| Hydrochloric Acid SCHEMBL15921544 | 0.70 | — | — | |
| SCHEMBL6039758 | 0.69 | CHRM1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102869-A | Urogenital disorders | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| US-4994453-A | Treating asthma, diabetes, obesity, immunosuppression | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| US-4925849-A | DIURETICS, HYPOTENSIVE AGENTS, CARIOTONIC AGENTS AND ANTIEDEMIC AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-15 | — | — | US | disclosed |