⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30172842 | 0.65 | — | — | |
| SCHEMBL8940156 | 0.56 | — | — | |
| SCHEMBL29212966 | 0.54 | — | — | |
| SCHEMBL7178578 | 0.54 | — | — | |
| SCHEMBL28695419 | 0.53 | — | — | |
| Water SCHEMBL28582929 | 0.52 | — | — | |
| SCHEMBL28484782 | 0.51 | — | — | |
| SCHEMBL5378825 | 0.49 | — | — | |
| SCHEMBL283912 | 0.49 | — | — | |
| SCHEMBL27799041 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135943-A | 1H-imidazole derivative compounds and pharmaceutical compositions containing the same | FERRER INTERNACIONAL S.A. (ES) | 1992-08-04 | — | — | US | disclosed |
| EP-0151477-B1 | 1H-IMIDAZOLE DERIVATIVES, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FERRER INTERNACIONAL, S.A. (ES) | 1990-09-12 | — | — | EP | disclosed |
| EP-0151477-A2 | 1H-Imidazole derivatives, a process for preparing them and pharmaceutical compositions containing them | FERRER INTERNACIONAL, S.A. (ES) | 1985-08-14 | — | — | EP | disclosed |