Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | XPO1 | O14980 | 1/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733072 | 1.00 | MEN1 (0.54) | MEN1PTGESXPO1SLC22A2ABCC4 | |
| SCHEMBL9733232 | 1.00 | MEN1 (0.54) | MEN1PTGESXPO1SLC22A2ABCC4 | |
| SCHEMBL9733925 | 0.92 | MEN1 (0.54) | MEN1PTGESXPO1SLC22A2ABCC4 | |
| SCHEMBL9733905 | 0.88 | MEN1 (0.56) | MEN1PTGESXPO1SLC22A2ABCC4 | |
| SCHEMBL9734934 | 0.88 | MEN1 (0.56) | MEN1PTGESXPO1SLC22A2ABCC4 | |
| SCHEMBL9733912 | 0.88 | MEN1 (0.56) | MEN1PTGESXPO1SLC22A2ABCC4 | |
| SCHEMBL9586130 | 0.87 | — | — | |
| SCHEMBL9734376 | 0.87 | CYSLTR1 (0.56) | MEN1PTGESXPO1SLC22A2ABCC4 | |
| SCHEMBL9394597 | 0.81 | CYSLTR1 (0.81) | MEN1PTGESXPO1SLC22A2ABCC4 | |
| SCHEMBL9394606 | 0.81 | CYSLTR1 (0.81) | MEN1PTGESXPO1SLC22A2ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096917-A | Antiallergens; treatment of asthma, hay fever, genetic disorders | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |