Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 6/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732705 | 0.93 | CACNA1C (0.55) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL9733144 | 0.91 | CACNA1C (0.62) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL9732611 | 0.89 | CACNA1F (0.52) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL9734218 | 0.87 | CACNA1F (0.60) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL9733309 | 0.86 | MEN1 (0.69) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL7265862 | 0.84 | CACNA1F (0.63) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL9732409 | 0.83 | CACNA1F (0.64) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL7160394 | 0.81 | CACNA1C (0.77) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL28612902 | 0.81 | MEN1 (0.76) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 | |
| SCHEMBL7266800 | 0.80 | CACNA1F (0.61) | CACNA1CCACNA1FCACNA1DCACNA1SCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158963-A | Cognition activators; improve brain function | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0411549-A1 | 1,4-dihydropyridine derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1991-02-06 | — | — | EP | disclosed |