Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 16/20 | 0.89 |
| ▸ | KCNH2 | Q12809 | 15/20 | 0.89 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10233871 | 0.94 | KCNJ1 (1.00) | KCNJ1KCNH2HRH3SIGMAR1 | |
| SCHEMBL9733429 | 0.85 | KCNH2 (0.88) | KCNJ1KCNH2HRH3SIGMAR1 | |
| SCHEMBL14904547 | 0.83 | KCNJ1 (0.78) | KCNJ1KCNH2HRH3SIGMAR1 | |
| SCHEMBL2731306 | 0.79 | KCNJ1 (1.00) | KCNJ1KCNH2HRH3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9732153 | 0.78 | KCNJ1 (0.67) | KCNJ1KCNH2HRH3 | |
| SCHEMBL9732081 | 0.76 | KCNH2 (0.61) | KCNJ1KCNH2 | |
| SCHEMBL3526680 | 0.74 | KCNJ1 (0.87) | KCNJ1KCNH2HRH3SIGMAR1 | |
| SCHEMBL5653299 | 0.74 | HRH3 (0.93) | KCNJ1KCNH2HRH3SIGMAR1 | |
| SCHEMBL3156895 | 0.74 | HRH3 (1.00) | KCNJ1KCNH2HRH3SIGMAR1 | |
| SCHEMBL9731809 | 0.73 | KCNJ1 (0.61) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112824-A | Benzofurazan compounds | MERCK & CO., INC. (US) | 1992-05-12 | — | — | US | disclosed |