⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973362 | 1.00 | — | — | |
| SCHEMBL8530079 | 0.76 | — | — | |
| SCHEMBL771486 | 0.74 | — | — | |
| SCHEMBL894183 | 0.74 | — | — | |
| SCHEMBL771487 | 0.74 | — | — | |
| SCHEMBL16938679 | 0.72 | — | — | |
| SCHEMBL10630483 | 0.70 | — | — | |
| SCHEMBL2224330 | 0.70 | — | — | |
| SCHEMBL9807068 | 0.70 | — | — | |
| SCHEMBL6937297 | 0.68 | TDP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304553-B2 | Method of forming oseltamivir and derivatives thereof | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-11-06 | — | — | US | disclosed |
| US-20110021762-A1 | METHOD OF FORMING OSELTAMIVIR AND DERIVATIVES THEREOF | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-01-27 | — | — | US | disclosed |
| WO-2009078813-A1 | METHOD OF FORMING OSELTAMIVIR AND DERIVATIVES THEREOF | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2009-06-25 | — | — | WO | disclosed |
| US-7094805-B2 | Total synthesis of merrilactone A | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2006-08-22 | — | — | US | disclosed |
| US-20040006121-A1 | Total synthesis of merrilactone A | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-01-08 | — | — | US | disclosed |
| WO-2003051303-A2 | THE TOTAL SYNTHESIS OF MERRILACTONE A | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-06-26 | — | — | WO | disclosed |
| US-5591854-A | CATALYTIC CONDENSATION OF DIENES AND VINYLDIAZOMETHANEESTERS | WAKE FOREST UNIVERSITY (US) | 1997-01-07 | — | — | US | disclosed |
| US-5155240-A | Process for producing optically active dihydropyran derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0246053-B1 | UNSATURATED SILYLATED VINYL ALCOHOL POLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |
| US-4739021-A | Unsaturated silylated vinyl alcohol polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-19 | — | — | US | disclosed |
| EP-0246053-A1 | Unsaturated silylated vinyl alcohol polymers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |