Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735297 | 0.86 | KHK (0.32) | TSHRTDP1MAPTSMN1; SMN2 | |
| SCHEMBL9617370 | 0.84 | KDM4E (0.43) | KDM4EGAATSHRTDP1MAPT | |
| SCHEMBL9738188 | 0.80 | KDM4E (0.38) | KDM4EGAA | |
| SCHEMBL11027970 | 0.77 | KDM4E (0.39) | KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL9735176 | 0.77 | MAPK1 (0.30) | TSHRTDP1SMN1; SMN2 | |
| SCHEMBL9787094 | 0.76 | KDM4E (0.38) | KDM4EGAA | |
| SCHEMBL11026783 | 0.73 | KDM4E (0.35) | KDM4EGAA | |
| SCHEMBL11027559 | 0.71 | KDM4E (0.38) | KDM4EGAA | |
| SCHEMBL11026950 | 0.71 | KDM4E (0.38) | KDM4EGAA | |
| SCHEMBL15358256 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138056-A | POLYCYANOPYRIMIDINES AND PROCESS FOR THEIR PREPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0462452-A1 | Polycyanopyrimidines and process for their preparation | BAYER AG (DE) | 1991-12-27 | — | — | EP | disclosed |