Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735186 | 0.86 | GRM2 (0.43) | ALDH1A1KMT2A | |
| SCHEMBL10993570 | 0.75 | MEN1 (0.40) | TSHRHPGDEHMT2ALDH1A1KMT2A | |
| SCHEMBL10341454 | 0.73 | KMT2A (0.49) | TSHRHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL6202791 | 0.73 | TSHR (0.58) | TSHRHPGDEHMT2ALDH1A1KMT2A | |
| SCHEMBL9766998 | 0.72 | HPGD (0.46) | TSHRHPGDEHMT2CACNA1GCACNA1H | |
| SCHEMBL21702593 | 0.72 | GBA1 (0.46) | TSHRHPGDEHMT2SIRT5KMT2A | |
| SCHEMBL20722526 | 0.72 | KMT2A (0.50) | TSHRHPGDEHMT2ALDH1A1SIRT5 | |
| SCHEMBL20722524 | 0.72 | KMT2A (0.50) | TSHRHPGDEHMT2ALDH1A1SIRT5 | |
| SCHEMBL20722523 | 0.72 | KMT2A (0.50) | TSHRHPGDEHMT2ALDH1A1SIRT5 | |
| SCHEMBL28610137 | 0.72 | GBA1 (0.46) | TSHRHPGDEHMT2SIRT5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114466-A | Plant growth regulators for weeds in a rice paddy | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-05-19 | — | — | US | disclosed |
| CN-1048032-A | 1-(3-substituted benzyl)-3-halo-4-(1-haloalkyl)-2-Pyrrolidone derivative and with its weedicide as effective constituent | MITSUI TOATSU CHEMICALS (JP) | 1990-12-26 | — | — | CN | disclosed |
| EP-0402893-A1 | 1-(3-substituted benzyl)-3-halogeno-4-(1-halogenoalkyl)-2-pyrrolidinone derivatives and herbicides containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-12-19 | — | — | EP | disclosed |
| US-4119636-A | FROM N-ALKENYL HALOMETHYL AMIDES, FERROUS ION CATALYST | STAUFFER CHEMICAL COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
| US-4069038-A | Acyclic and alicyclic N-substituted halo-2-pyrrolidinones and their utility as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1978-01-17 | — | — | US | disclosed |