Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11965213 | 0.83 | NPC1 (0.57) | NPC1L3MBTL1TRPM8CYP1A2TDP1 | |
| SCHEMBL12693652 | 0.78 | NPC1 (0.72) | NPC1L3MBTL1TRPM8CYP1A2TDP1 | |
| SCHEMBL4583626 | 0.77 | AOC3 (0.61) | AOC3TDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2093623 | 0.77 | AOC3 (0.61) | NPC1L3MBTL1AOC3TDP1ALDH1A1 | |
| SCHEMBL14393835 | 0.77 | AOC3 (0.61) | NPC1L3MBTL1AOC3TDP1ALDH1A1 | |
| SCHEMBL16901650 | 0.77 | AOC3 (0.61) | NPC1L3MBTL1AOC3TDP1ALDH1A1 | |
| SCHEMBL7748541 | 0.77 | NPC1 (0.57) | NPC1L3MBTL1TRPM8CYP1A2TDP1 | |
| SCHEMBL7748543 | 0.77 | NPC1 (0.57) | NPC1L3MBTL1TRPM8CYP1A2TDP1 | |
| SCHEMBL10575087 | 0.76 | NPC1 (0.60) | NPC1L3MBTL1TRPM8CYP1A2TDP1 | |
| SCHEMBL10575096 | 0.76 | NPC1 (0.60) | NPC1L3MBTL1TRPM8CYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132433-A | PROCESS FOR THE PREPARATION OF CLAUSENAMIDE AND NEOCLAUSENAMIDE, AND DERIVATIVES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 1992-07-21 | — | — | US | disclosed |