Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736855 | 0.83 | — | — | |
| SCHEMBL9737885 | 0.76 | CYP3A4 (0.39) | — | |
| SCHEMBL9737899 | 0.76 | CYP3A4 (0.39) | — | |
| SCHEMBL9738321 | 0.72 | TSHR (0.36) | ALDH1A1 | |
| SCHEMBL5404053 | 0.72 | ECE1 (0.33) | — | |
| SCHEMBL5404048 | 0.72 | ECE1 (0.33) | — | |
| SCHEMBL9738976 | 0.70 | — | — | |
| SCHEMBL9737560 | 0.70 | — | — | |
| SCHEMBL15380354 | 0.66 | POLB (0.41) | ALDH1A1 | |
| SCHEMBL14012780 | 0.64 | POLB (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251164-B1 | NEW CHIRAL PHOSPHINOPYRROLIDINE COMPOUNDS AND THEIR USE FOR ASYMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | Achiwa, Kazuo (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-4879389-A | HYDROGENATION CATALYSTS | ACHIWA KAZUO (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0251164-A2 | New chiral phosphinopyrrolidine compounds and their use for asymetric synthesis of optically active compounds | Achiwa, Kazuo (JP) | 1988-01-07 | — | — | EP | disclosed |