⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746055 | 0.97 | — | — | |
| SCHEMBL3475935 | 0.95 | — | — | |
| SCHEMBL3472703 | 0.95 | — | — | |
| SCHEMBL29617172 | 0.82 | — | — | |
| SCHEMBL30487039 | 0.80 | TSHR (0.37) | — | |
| SCHEMBL27911802 | 0.79 | — | — | |
| SCHEMBL2138479 | 0.76 | — | — | |
| SCHEMBL11747797 | 0.74 | — | — | |
| SCHEMBL8834932 | 0.72 | TSHR (0.32) | — | |
| SCHEMBL11100252 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251164-B1 | NEW CHIRAL PHOSPHINOPYRROLIDINE COMPOUNDS AND THEIR USE FOR ASYMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | Achiwa, Kazuo (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-4985567-A | Ligand for a Metal Complex Catalyst | KAZUO ACHIWA (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4879389-A | HYDROGENATION CATALYSTS | ACHIWA KAZUO (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0336123-A2 | New chiral phosphinopyrrolidine compounds and their use for asymmetric synthesis of optically active compounds | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1989-10-11 | — | — | EP | disclosed |
| EP-0251164-A2 | New chiral phosphinopyrrolidine compounds and their use for asymetric synthesis of optically active compounds | Achiwa, Kazuo (JP) | 1988-01-07 | — | — | EP | disclosed |
| US-4124533-A | HYDROGENATION CATALYSTS | MONSANTO COMPANY (US) | 1978-11-07 | — | — | US | disclosed |
| US-4005127-A | L-Dopa process and intermediates | MONSANTO COMPANY (US) | 1977-01-25 | — | — | US | disclosed |