Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735478 | 0.86 | TDP1 (0.43) | TDP1 | |
| SCHEMBL3489131 | 0.85 | TDP1 (0.47) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL845645 | 0.85 | TDP1 (0.47) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL669311 | 0.85 | TDP1 (0.47) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL28554669 | 0.85 | TDP1 (0.47) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL11574659 | 0.84 | TDP1 (0.69) | TDP1 | |
| Bromide SCHEMBL1290128 | 0.84 | TDP1 (0.46) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| Bromide SCHEMBL1290055 | 0.84 | TDP1 (0.46) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL315060 | 0.82 | TDP1 (0.66) | TDP1 | |
| SCHEMBL9679260 | 0.80 | TDP1 (0.49) | TDP1USP2CYP3A4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125711-A | Process for preparing auranofin | SMITHKLINE CORPORATION (US) | 1978-11-14 | — | — | US | claimed |
| CN-116891510-B | Glycosylated chiral binuclear Ir (III) metal-organic double helix structure compound and preparation method and application thereof | 大连理工大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-116891510-A | Glycosylated chiral binuclear Ir (III) metal-organic double helix structure compound and preparation method and application thereof | 大连理工大学 | 2023-10-17 | — | — | CN | disclosed |
| US-5091523-A | Bactericides, antitumor agent | GEORGETOWN UNIVERSITY (US) | 1992-02-25 | — | — | US | disclosed |
| US-4125711-A | Process for preparing auranofin | SMITHKLINE CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |
| US-4125711-A | Process for preparing auranofin | SMITHKLINE CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |