SCHEMBL9738167

SCHEMBL9738167

c1ccc(C[C@H]2CO[C@H](c3nc(-c4ccccc4)c(-c4ccccc4)[nH]3)OC2)cc1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 11/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9737570 1.00 SOAT1 (0.60) SOAT1
SCHEMBL9737576 1.00 SOAT1 (0.60) SOAT1
SCHEMBL5771859 0.87 MAPK14 (0.56) SOAT1
SCHEMBL9738249 0.81 SOAT1 (0.69) SOAT1
SCHEMBL4120287 0.78 SOAT1 (0.68) SOAT1
SCHEMBL7075191 0.75 SOAT1 (1.00) SOAT1
SCHEMBL9737518 0.74 SOAT1 (1.00) SOAT1
SCHEMBL9740337 0.74 SOAT1 (0.77) SOAT1
Hydrochloric Acid SCHEMBL9737937 0.74 SOAT1 (0.97) SOAT1
SCHEMBL9738287 0.73 SOAT1 (0.72) SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102900-A Antilipemic and anticholesterol agents RHONE-POULENC RORER S.A. (FR) 1992-04-07 US claimed
US-5102900-A Antilipemic and anticholesterol agents RHONE-POULENC RORER S.A. (FR) 1992-04-07 US disclosed