SCHEMBL9738839

SCHEMBL9738839

CCCCNC(=O)Oc1ccc2c(ccn2N(CCC)c2ccncc2F)c1

nearest known ligand 0.75

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BCHE P06276 4/20 0.75
SLC6A2 P23975 3/20 0.48
LIPE Q05469 1/20 0.40
FAAH O00519 1/20 0.38
MGLL Q99685 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9671984 0.99 BCHE (0.74) BCHESLC6A2LIPEFAAHMGLL
SCHEMBL9738698 0.97 BCHE (0.70) BCHESLC6A2MGLL
Hydrochloric Acid SCHEMBL9671917 0.96 BCHE (0.69) BCHESLC6A2MGLL
SCHEMBL8539324 0.90 BCHE (0.72) BCHESLC6A2
SCHEMBL8543791 0.86 BCHE (1.00) BCHESLC6A2LIPEFAAH
SCHEMBL9738440 0.86 SLC6A2 (0.66) BCHESLC6A2MGLL
Hydrochloric Acid SCHEMBL8537931 0.85 SLC6A2 (0.65) BCHESLC6A2MGLL
SCHEMBL8537919 0.83 BCHE (0.94) BCHEMGLL
SCHEMBL8539705 0.82 SLC6A2 (0.64) BCHESLC6A2MGLL
SCHEMBL8544459 0.81 SLC6A2 (0.67) BCHESLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102891-A Useful for treating various memory dysfunctions such as alzheimer's disease HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1992-04-07 US claimed
US-5102891-A Useful for treating various memory dysfunctions such as alzheimer's disease HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1992-04-07 US disclosed