Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739036 | 0.87 | SLC6A2 (0.47) | SLC6A2LIPETSHRCYP2D6SMN1; SMN2 | |
| SCHEMBL8541743 | 0.80 | SLC6A2 (0.56) | SLC6A2KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8539248 | 0.79 | EPHX1 (0.50) | SLC6A2FAAH | |
| SCHEMBL8539243 | 0.77 | SLC6A2 (0.54) | SLC6A2NPSR1LIPEKDM4EALDH1A1 | |
| SCHEMBL8543202 | 0.77 | SLC6A2 (0.49) | SLC6A2GAAKDM4EMAPTCYP2C9 | |
| SCHEMBL8539588 | 0.75 | SLC6A2 (0.50) | SLC6A2 | |
| SCHEMBL9672902 | 0.74 | SLC6A2 (0.62) | SLC6A2LIPE | |
| Hydrochloric Acid SCHEMBL8544161 | 0.74 | SLC6A2 (0.49) | SLC6A2 | |
| SCHEMBL8543206 | 0.73 | SLC6A2 (0.44) | SLC6A2CYP2C9 | |
| SCHEMBL9672239 | 0.72 | SLC6A2 (0.55) | SLC6A2LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102891-A | Useful for treating various memory dysfunctions such as alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-04-07 | — | — | US | disclosed |