Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.69 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KLK7 | P49862 | 1/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394900 | 1.00 | PREP (0.69) | PREPCTRB1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL8160599 | 1.00 | PREP (0.69) | PREPCTRB1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL8160600 | 1.00 | PREP (0.69) | PREPCTRB1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL17459445 | 0.97 | PREP (0.71) | PREPCTRB1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL20678314 | 0.97 | PREP (0.71) | PREPCTRB1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL17459413 | 0.97 | PREP (0.71) | PREPCTRB1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL18093534 | 0.97 | PREP (0.71) | PREPCTRB1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL17459415 | 0.97 | PREP (0.71) | PREPCTRB1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL9554796 | 0.97 | PREP (0.71) | PREPCTRB1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL630208 | 0.94 | PREP (0.62) | PREPCTRB1ALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106982-A | Cognition activators | E. R. SQUIBB & SONS, INC. (US) | 1992-04-21 | — | — | US | disclosed |