Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC33A1 | O00400 | 3/20 | 0.34 |
| ▸ | GCGR | P47871 | 4/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738105 | 0.92 | SLC33A1 (0.34) | SLC33A1GCGRTRPV1KCNJ6KCNJ5 | |
| SCHEMBL9738589 | 0.91 | SLC33A1 (0.34) | SLC33A1TRPV1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL9739848 | 0.91 | SLC33A1 (0.35) | SLC33A1AGTR1AGTR2 | |
| SCHEMBL9738469 | 0.91 | SLC33A1 (0.35) | SLC33A1GCGRAGTR1AGTR2 | |
| SCHEMBL9552226 | 0.91 | SLC33A1 (0.36) | SLC33A1TRPV1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL9739582 | 0.90 | SLC33A1 (0.36) | SLC33A1AGTR1AGTR2 | |
| SCHEMBL9552886 | 0.89 | SLC33A1 (0.35) | SLC33A1GCGRTRPV1KCNJ6KCNJ5 | |
| SCHEMBL9737781 | 0.87 | SLC33A1 (0.35) | SLC33A1AGTR1AGTR2 | |
| SCHEMBL9738379 | 0.86 | SLC33A1 (0.36) | SLC33A1AGTR1AGTR2 | |
| SCHEMBL9553347 | 0.86 | SLC33A1 (0.35) | SLC33A1TRPV1AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | claimed |
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | disclosed |