Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL21961942 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL28070973 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL2959365 | 0.96 | FFAR3 (0.50) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL25333160 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL1879030 | 0.92 | FFAR3 (0.64) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL8888237 | 0.92 | FFAR3 (0.64) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL139024 | 0.92 | FFAR3 (0.64) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL17909908 | 0.92 | FFAR3 (0.64) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL2516097 | 0.92 | FFAR3 (0.64) | FFAR3LCKFYNTSHRLMNA | |
| Acetic Acid SCHEMBL1578192 | 0.92 | FFAR3 (0.64) | FFAR3LCKFYNTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546455-B2 | Expanded polystyrene solubilization method | ESKA (FR) | 2013-10-01 | — | — | US | disclosed |
| CN-101699553-B | Display device, its driving method, and electronic equipment | SEMICONDUCTOR ENERGY LAB | 2012-03-21 | — | — | CN | disclosed |
| US-20110021647-A1 | Expanded polystyrene solubilization method | ESKA (FR) | 2011-01-27 | — | — | US | disclosed |
| US-4626453-A | Coating compositions and method for improving the properties of coated substrates | COATINGS FOR INDUSTRY, INC. (US) | 1986-12-02 | — | — | US | disclosed |