Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.67 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636320 | 1.00 | CYP4F2 (0.67) | CYP4F2CYP4A11ALDH1A1CA2POLB | |
| Acetic Acid SCHEMBL20876688 | 0.96 | CYP4F2 (0.62) | CYP4F2CYP4A11ALDH1A1CA2POLB | |
| SCHEMBL2426350 | 0.85 | CYP4F2 (0.51) | CYP4F2CYP4A11ALDH1A1TSHRHPGD | |
| SCHEMBL9129772 | 0.85 | CYP4F2 (0.52) | CYP4F2CYP4A11ALDH1A1POLBMEN1 | |
| SCHEMBL4675667 | 0.85 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1CA2HSD11B1 | |
| SCHEMBL29588217 | 0.84 | CYP4F2 (0.47) | CYP4F2CYP4A11CA2HSD11B1MEN1 | |
| SCHEMBL5848088 | 0.84 | CYP4F2 (0.47) | CYP4F2CYP4A11CA2HSD11B1MEN1 | |
| SCHEMBL5848091 | 0.84 | CYP4F2 (0.47) | CYP4F2CYP4A11CA2HSD11B1MEN1 | |
| SCHEMBL4926783 | 0.84 | CYP4F2 (0.47) | CYP4F2CYP4A11CA2HSD11B1MEN1 | |
| SCHEMBL12660944 | 0.83 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089637-A | PROCESS AND INTERMEDIATES FOR 2R-BENZYL-CHROMAN-6-CARBALDEHYDE | PFIZER INC. (US) | 1992-02-18 | — | — | US | disclosed |