Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742000 | 0.90 | PNP (0.34) | PNP | |
| SCHEMBL9740365 | 0.89 | PNP (0.36) | PNPFGFR1MEN1ALDH1A1HPGD | |
| SCHEMBL9663817 | 0.85 | PNP (0.36) | PNPMEN1ALDH1A1KMT2A | |
| SCHEMBL9663073 | 0.81 | BLM (0.47) | PNPFGFR1MEN1ALDH1A1KMT2A | |
| SCHEMBL9741529 | 0.77 | PNP (0.59) | PNPMEN1ALDH1A1KMT2A | |
| SCHEMBL9741665 | 0.76 | PNP (0.58) | PNPMEN1ALDH1A1KMT2A | |
| SCHEMBL9741386 | 0.76 | PNP (0.58) | PNPMEN1ALDH1A1KMT2A | |
| SCHEMBL9741381 | 0.76 | PNP (0.58) | PNPMEN1ALDH1A1KMT2A | |
| SCHEMBL11011339 | 0.75 | PNP (0.33) | PNPMEN1ALDH1A1KMT2A | |
| SCHEMBL9740954 | 0.73 | PNP (0.59) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098906-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4921859-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4918219-A | Glycerine derivatives | WARNER-LAMBERT COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| US-4806642-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0145207-B1 | PURINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0145207-A1 | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1985-06-19 | — | — | EP | disclosed |