Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | CDC7 | O00311 | 2/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741027 | 0.90 | NPSR1 (0.44) | NPSR1ALDH1A1TDP1HTTHSD17B10 | |
| SCHEMBL9741899 | 0.88 | NPSR1 (0.43) | NPSR1ALDH1A1TDP1HTTHSD17B10 | |
| SCHEMBL9741511 | 0.84 | NR2E3 (0.41) | NPSR1ALDH1A1TDP1HTTHSD17B10 | |
| SCHEMBL9741908 | 0.82 | NR2E3 (0.46) | NPSR1ALDH1A1TDP1HTTHSD17B10 | |
| SCHEMBL9741863 | 0.82 | NPSR1 (0.39) | NPSR1ALDH1A1TDP1HTTHSD17B10 | |
| SCHEMBL9741437 | 0.81 | NR2E3 (0.45) | NPSR1ALDH1A1TDP1HTTHSD17B10 | |
| SCHEMBL9426904 | 0.80 | HSD17B10 (0.50) | ALDH1A1TDP1HTTHSD17B10NPC1 | |
| SCHEMBL29838045 | 0.73 | NPSR1 (0.42) | NPSR1ALDH1A1HSD17B10NPC1MAPT | |
| SCHEMBL26694307 | 0.73 | NPSR1 (0.42) | NPSR1ALDH1A1HSD17B10NPC1MAPT | |
| SCHEMBL9427382 | 0.71 | NR2E3 (0.48) | NPSR1ALDH1A1TDP1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006965-A1 | HERBICIDAL SULFONYLUREA DERIVATIVES | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1992-04-30 | — | — | WO | disclosed |