⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1065269 | 0.64 | — | — | |
| SCHEMBL187430 | 0.57 | MEN1 (0.35) | — | |
| SCHEMBL1424312 | 0.57 | — | — | |
| SCHEMBL1561112 | 0.57 | — | — | |
| SCHEMBL1521804 | 0.57 | — | — | |
| SCHEMBL5949910 | 0.55 | — | — | |
| SCHEMBL7454796 | 0.53 | — | — | |
| SCHEMBL7804792 | 0.52 | MEN1 (0.34) | — | |
| SCHEMBL2267657 | 0.50 | MEN1 (0.33) | — | |
| SCHEMBL196616 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531508-A1 | PYRROLO [ 2, 3 - D]PYRIMIDINE UREA COMPOUNDS AS JAK INHIBITORS | Pfizer Inc. (US) | 2012-12-12 | — | — | EP | claimed |
| US-20120309776-A1 | PYRROLO[2,3-D]PYRIMIDINE UREA COMPOUNDS AS JAK INHIBITORS | PFITZER INC. | 2012-12-06 | — | — | US | claimed |
| WO-2011097087-A1 | PYRROLO [ 2, 3 - D] PYRIMIDINE UREA COMPOUNDS AS JAK INHIBITORS | PFIZER INC. (US) | 2011-08-11 | — | — | WO | claimed |
| US-5159070-A | Process for the preparation of derivative of 7-[(2-hydroxyimino)-acetamido]-cephalosporanic acid | ROUSSEL UCLAF (FR) | 1992-10-27 | — | — | US | claimed |
| US-4439433-A | CEPHALOSPORIN ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1984-03-27 | — | — | US | claimed |
| US-4287193-A | ANTIBIOTIC DERIVATIVES OF CEPHALOSPORANIC ACID | ROUSSEL UCLAF (FR) | 1981-09-01 | — | — | US | claimed |
| US-20130131113-A1 | PYRIDONE GLUCOKINASE ACTIVATORS | HOFFMANN-LA ROCHE INC. (US) | 2013-05-23 | — | — | US | disclosed |
| EP-2582706-A1 | 3-OXO-3,9-DIHYDRO-1H-CHROMENO[2,3-C]PYRROLES AS GLUCOKINASE ACTIVATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-04-24 | — | — | EP | disclosed |
| EP-2531508-A1 | PYRROLO [ 2, 3 - D]PYRIMIDINE UREA COMPOUNDS AS JAK INHIBITORS | Pfizer Inc. (US) | 2012-12-12 | — | — | EP | disclosed |
| US-20120309776-A1 | PYRROLO[2,3-D]PYRIMIDINE UREA COMPOUNDS AS JAK INHIBITORS | PFITZER INC. | 2012-12-06 | — | — | US | disclosed |
| US-8258134-B2 | Pyridazinone glucokinase activators | HOFFMANN-LA ROCHE INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-8178689-B2 | Tricyclic compounds | HOFFMAN-LA ROCHE INC. (US) | 2012-05-15 | — | — | US | disclosed |
| EP-2274297-B1 | PYRROLIDINONE GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2012-05-09 | — | — | EP | disclosed |
| US-4900728-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1990-02-13 | — | — | US | disclosed |
| US-4439433-A | CEPHALOSPORIN ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1984-03-27 | — | — | US | disclosed |
| US-4385181-A | CHAMICAL INTERMEDIATES FOR CEPHALOSPORINS | RHONE POULENC INDUSTRIES (FR) | 1983-05-24 | — | — | US | disclosed |
| US-4374834-A | CEPHEM ANTIBIOTICS | Uclaf, Roussel (FR) | 1983-02-22 | — | — | US | disclosed |
| US-4307116-A | BACTERICIDES | RHONE-POULENC INDUSTRIES (FR) | 1981-12-22 | — | — | US | disclosed |
| US-4287193-A | ANTIBIOTIC DERIVATIVES OF CEPHALOSPORANIC ACID | ROUSSEL UCLAF (FR) | 1981-09-01 | — | — | US | disclosed |
| EP-0023453-A1 | Process for the preparation of derivatives of 7-(2-aryl)-2-hydroxyimino-acetamido cephalosporanic acid | ROUSSEL-UCLAF (FR) | 1981-02-04 | — | — | EP | disclosed |