Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.48 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324110 | 1.00 | TACR1 (0.48) | TACR1MRGPRX1HTR7MEN1KMT2A | |
| SCHEMBL9767694 | 0.86 | TACR1 (0.38) | TACR1MRGPRX1HTR7BCHEACHE | |
| Water SCHEMBL9742198 | 0.86 | TACR1 (0.60) | TACR1 | |
| SCHEMBL9325044 | 0.83 | TACR1 (0.58) | TACR1HTR7 | |
| SCHEMBL9321890 | 0.82 | TACR1 (0.56) | TACR1 | |
| SCHEMBL9322762 | 0.81 | TACR1 (0.51) | TACR1 | |
| SCHEMBL9324189 | 0.80 | TACR1 (0.53) | TACR1 | |
| Hydrochloric Acid SCHEMBL9323145 | 0.78 | TACR1 (0.56) | TACR1 | |
| SCHEMBL9321776 | 0.78 | TACR1 (0.52) | TACR1 | |
| SCHEMBL9322963 | 0.77 | TACR1 (0.53) | TACR1BCHEACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162339-A | Substance P Antagonists, Gastrointestinal and Central Nervous System Disorders, Antiinflammatory Agents, Analgesics | PFIZER INC. (US) | 1992-11-10 | — | — | US | disclosed |