Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 8/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743138 | 1.00 | TSHR (0.54) | TSHRHSD17B10RARBASIC3HRH3 | |
| SCHEMBL9742431 | 0.99 | HSD17B10 (0.56) | TSHRHSD17B10RARBASIC3HRH3 | |
| SCHEMBL9743873 | 0.99 | HSD17B10 (0.56) | TSHRHSD17B10RARBASIC3HRH3 | |
| SCHEMBL9745311 | 0.99 | HSD17B10 (0.56) | TSHRHSD17B10RARBASIC3HRH3 | |
| SCHEMBL9743775 | 0.97 | TSHR (0.56) | TSHRHSD17B10RARBASIC3HRH3 | |
| SCHEMBL9741967 | 0.96 | HSD17B10 (0.59) | TSHRHSD17B10RARBASIC3HRH3 | |
| SCHEMBL9742379 | 0.96 | TSHR (0.48) | TSHRHSD17B10RARBASIC3HRH3 | |
| SCHEMBL9743082 | 0.96 | TSHR (0.55) | TSHRHSD17B10RARBASIC3HRH3 | |
| SCHEMBL9744004 | 0.96 | HSD17B10 (0.59) | TSHRHSD17B10RARBASIC3HRH3 | |
| SCHEMBL9742426 | 0.96 | HSD17B10 (0.59) | TSHRHSD17B10RARBASIC3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084204-A | Naphthylacetylenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-01-28 | — | — | US | disclosed |