SCHEMBL9743702

SCHEMBL9743702

O=C(O)CNc1ccc(O)cc1.O=C(O)CNc1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 2/20 0.52
HIF1A Q16665 1/20 0.47
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
CA2 P00918 3/20 0.46
CAMK2A Q9UQM7 1/20 0.46
MAPT P10636 4/20 0.45
MEN1 O00255 3/20 0.45
ALDH1A1 P00352 3/20 0.45
KMT2A Q03164 3/20 0.45
CA1 P00915 2/20 0.45
PEPD P12955 1/20 0.45
CA12 O43570 1/20 0.45
BRD4 O60885 1/20 0.45
NR1I2 O75469 1/20 0.45
MB P02144 1/20 0.45
CA3 P07451 1/20 0.45
CYP3A4 P08684 1/20 0.45
RARG P13631 1/20 0.45
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9745051 1.00 CYP1A1 (0.52) CYP1A1HIF1AMAOAMAOBCA2
SCHEMBL22354 1.00 CYP1A1 (0.52) CYP1A1HIF1AMAOAMAOBCA2
Hydrochloric Acid SCHEMBL11326485 1.00 CYP1A1 (0.52) CYP1A1HIF1AMAOAMAOBCA2
SCHEMBL9745182 1.00 CYP1A1 (0.52) CYP1A1HIF1AMAOAMAOBCA2
Hydrochloric Acid SCHEMBL4820901 1.00 CYP1A1 (0.52) CYP1A1HIF1AMAOAMAOBCA2
Benzene SCHEMBL11193867 0.98 CYP1A1 (0.50) CYP1A1HIF1AMAOAMAOBCA2
Ammonia Solution, Strong SCHEMBL10883600 0.98 CYP1A1 (0.50) CYP1A1HIF1AMAOAMAOBCA2
SCHEMBL11973849 0.98 CYP1A1 (0.50) CYP1A1HIF1AMAOAMAOBCA2
SCHEMBL1578385 0.98 CYP1A1 (0.50) CYP1A1HIF1AMAOAMAOBCA2
Hypochlorous Acid SCHEMBL11320999 0.96 CYP1A1 (0.48) CYP1A1HIF1AMAOAMAOBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5120855-A Formation of hydroxyaromatic ketoacetal from a hydroxyaromatic methylketone and production of 5-(4'-hydroxyphenyl)hydantoin and Dp-hydroxyphenylglycine from 4-hydroxyacetophenone HOECHST CELANESE CORPORATION (US) 1992-06-09 US disclosed