Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.59 |
| ▸ | APEX1 | P27695 | 4/20 | 0.59 |
| ▸ | APAF1 | O14727 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.59 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.59 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | FAP | Q12884 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743996 | 1.00 | PTGS1 (0.61) | PTGS1TDP1APEX1APAF1LMNA | |
| SCHEMBL9482824 | 0.91 | PTGS1 (0.72) | PTGS1TDP1APEX1APAF1LMNA | |
| SCHEMBL9482817 | 0.91 | PTGS1 (0.72) | PTGS1TDP1APEX1APAF1LMNA | |
| SCHEMBL9482324 | 0.90 | TDP1 (0.73) | PTGS1TDP1APEX1APAF1LMNA | |
| SCHEMBL9482340 | 0.90 | TDP1 (0.73) | PTGS1TDP1APEX1APAF1LMNA | |
| Hydrochloric Acid SCHEMBL9481307 | 0.90 | TDP1 (0.73) | PTGS1TDP1APEX1APAF1LMNA | |
| Hydrochloric Acid SCHEMBL9481300 | 0.90 | TDP1 (0.73) | PTGS1TDP1APEX1APAF1LMNA | |
| SCHEMBL9481582 | 0.90 | TDP1 (0.65) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9481565 | 0.90 | TDP1 (0.65) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL10817602 | 0.87 | TDP1 (0.78) | PTGS1TDP1APEX1APAF1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110921-A | Bactericides | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
| US-4960889-A | CEPHALOSPORIN INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| US-4731443-A | 7-acylamino-3-vinylcephalosporanic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-15 | — | — | US | disclosed |
| US-4487927-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-12-11 | — | — | US | disclosed |