Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.53 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 3/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744011 | 0.97 | NR1I2 (0.54) | NR1I2PPARGMAPTSLC22A6SLC22A8 | |
| SCHEMBL9326225 | 0.92 | NR1I2 (0.53) | NR1I2PPARGMAPTSLC22A6SLC22A8 | |
| SCHEMBL9551564 | 0.90 | NR1I2 (0.62) | NR1I2PPARGMAPTSLC22A6SLC22A8 | |
| SCHEMBL9551553 | 0.90 | NR1I2 (0.62) | NR1I2PPARGMAPTSLC22A6SLC22A8 | |
| SCHEMBL9744042 | 0.88 | NR1I2 (0.54) | NR1I2PPARGMAPTSLC22A6SLC22A8 | |
| SCHEMBL9021446 | 0.86 | NR1I2 (0.47) | NR1I2PPARGMAPTSLC22A6SLC22A8 | |
| SCHEMBL9021180 | 0.86 | NR1I2 (0.62) | NR1I2PPARGMAPTSLC22A6SLC22A8 | |
| SCHEMBL9745801 | 0.85 | TDP1 (0.63) | NR1I2PPARGMAPTSLC22A6SLC22A8 | |
| SCHEMBL9329763 | 0.85 | NR1I2 (0.54) | NR1I2PPARGMAPTSLC22A6SLC22A8 | |
| SCHEMBL9021107 | 0.84 | NR1I2 (0.53) | NR1I2PPARGMAPTSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147871-A | Anti-bacterial cephalosporin compounds | HOFFMANN LA-ROCHE, INC. (US) | 1992-09-15 | — | — | US | claimed |