Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744185 | 1.00 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3DRD2CYP2C9 | |
| SCHEMBL9742377 | 0.99 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3DRD2CYP2C9 | |
| SCHEMBL9742814 | 0.99 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3DRD2CYP2C9 | |
| SCHEMBL9743270 | 0.99 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3DRD2CYP2C9 | |
| SCHEMBL9743267 | 0.99 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3DRD2CYP2C9 | |
| SCHEMBL9742382 | 0.99 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3DRD2CYP2C9 | |
| SCHEMBL9742806 | 0.99 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3DRD2CYP2C9 | |
| SCHEMBL9743813 | 0.99 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3DRD2CYP2C9 | |
| SCHEMBL9743818 | 0.99 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3DRD2CYP2C9 | |
| SCHEMBL9743959 | 0.97 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3DRD2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084204-A | Naphthylacetylenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-01-28 | — | — | US | disclosed |