Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743234 | 1.00 | FFAR1 (0.46) | FFAR1HSD17B10TSHRHTR2APLK1 | |
| SCHEMBL9742589 | 1.00 | FFAR1 (0.46) | FFAR1HSD17B10TSHRHTR2APLK1 | |
| SCHEMBL9743698 | 0.99 | FFAR1 (0.47) | FFAR1HSD17B10TSHRHTR2APLK1 | |
| SCHEMBL9741999 | 0.96 | TSHR (0.52) | FFAR1HSD17B10TSHRHTR2APLK1 | |
| SCHEMBL9742386 | 0.96 | TSHR (0.52) | FFAR1HSD17B10TSHRHTR2APLK1 | |
| SCHEMBL9743224 | 0.96 | TSHR (0.52) | FFAR1HSD17B10TSHRHTR2APLK1 | |
| SCHEMBL9742469 | 0.95 | TSHR (0.50) | FFAR1HSD17B10TSHRHTR2APLK1 | |
| SCHEMBL9742134 | 0.94 | FFAR1 (0.48) | FFAR1ALDH1A1LMNACYP3A4MEN1 | |
| SCHEMBL9742267 | 0.92 | PPARG (0.46) | HSD17B10TSHRHTR2ATHRBALDH1A1 | |
| SCHEMBL9742176 | 0.92 | PPARG (0.46) | HSD17B10TSHRHTR2ATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084204-A | Naphthylacetylenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-01-28 | — | — | US | disclosed |