SCHEMBL9744443

SCHEMBL9744443

CCCCCCCCC(c1cccc2ccccc12)C([SiH2]O)(c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CNR2 P34972 6/20 0.34
CNR1 P21554 4/20 0.34
SLC6A4 P31645 1/20 0.33
KCNH2 Q12809 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL9244262 0.78 KDM4E (0.40) KDM4EKMT2AL3MBTL1CNR2CNR1
Hydrochloric Acid SCHEMBL9516629 0.78 KDM4E (0.40) KDM4EKMT2AL3MBTL1CNR2CNR1
Hydrochloric Acid SCHEMBL9347038 0.76 KDM4E (0.39) KDM4EKMT2AL3MBTL1CNR2CNR1
Hydrochloric Acid SCHEMBL11127238 0.76 KDM4E (0.40) KDM4EKMT2AL3MBTL1SLC6A4GAA
Hydrochloric Acid SCHEMBL11129575 0.76 KDM4E (0.40) KDM4EKMT2AL3MBTL1SLC6A4GAA
Water SCHEMBL11428305 0.76 KDM4E (0.40) KDM4EKMT2AL3MBTL1CNR2CNR1
Water SCHEMBL11433319 0.76 KDM4E (0.40) KDM4EKMT2AL3MBTL1CNR2CNR1
Water SCHEMBL11433831 0.76 KDM4E (0.40) KDM4EKMT2AL3MBTL1CNR2CNR1
Water SCHEMBL11427301 0.76 KDM4E (0.40) KDM4EKMT2AL3MBTL1CNR2CNR1
Hydrochloric Acid SCHEMBL11129284 0.76 KDM4E (0.40) KDM4EKMT2AL3MBTL1SLC6A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5099006-A ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates RHONE-POULENC INC. (US) 1992-03-24 US disclosed
EP-0324671-A2 Alkoxy-type derivatives of trivalent metals of group 3b, and their preparation RHONE-POULENC CHIMIE (FR) 1989-07-19 EP disclosed
EP-0319383-A2 Process for the fabrication of cerium hydrocarbonsilyloxides by transetherification of cerium alkoxides RHONE-POULENC CHIMIE (FR) 1989-06-07 EP disclosed
EP-0319384-A2 Cerium hydrocarbonsilyloxydes and process for their manufacture RHONE-POULENC CHIMIE (FR) 1989-06-07 EP disclosed