Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 17/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | HMGCR | P04035 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744468 | 1.00 | GCGR (0.54) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9744297 | 0.92 | ESR1 (0.51) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9744292 | 0.92 | ESR1 (0.51) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9744437 | 0.89 | GCGR (0.58) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8973684 | 0.88 | ESR1 (0.62) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL7561153 | 0.88 | ESR1 (0.62) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9744058 | 0.85 | GCGR (0.43) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9745542 | 0.83 | GCGR (0.52) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9153492 | 0.81 | ESR1 (0.52) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8953459 | 0.81 | ESR1 (0.52) | GCGRESR1HMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145857-A | HMG-COA REDUCTASE-INHIBITING SUBSTITUTED AMINO-PYRIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0416383-A2 | Substituted aminopyridines | BAYER AG (DE) | 1991-03-13 | — | — | EP | disclosed |