SCHEMBL9744461

SCHEMBL9744461

O=c1oc(-c2ccccc2)nc2cc(F)ccc12

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.69
HPN P05981 1/20 0.56
NPC1 O15118 5/20 0.56
RAB9A P51151 4/20 0.56
RXFP1 Q9HBX9 1/20 0.56
F2 P00734 2/20 0.54
C1R P00736 2/20 0.52
ALDH1A1 P00352 6/20 0.52
MAPT P10636 5/20 0.52
KDM4E B2RXH2 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
LMNA P02545 2/20 0.52
KMT2A Q03164 3/20 0.52
HPGD P15428 3/20 0.52
APEX1 P27695 1/20 0.52
MEN1 O00255 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
TP53 P04637 2/20 0.49
MGLL Q99685 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12927374 0.92 ELANE (0.56) ELANEHPNNPC1RAB9ARXFP1
SCHEMBL17554091 0.85 F2 (0.69) ELANEHPNNPC1RAB9AF2
SCHEMBL913448 0.84 ELANE (0.78) ELANENPC1RAB9ARXFP1F2
SCHEMBL10780103 0.84 ELANE (0.77) ELANEHPNNPC1RAB9ARXFP1
SCHEMBL5921381 0.84 ELANE (0.71) ELANEHPNNPC1RAB9ARXFP1
SCHEMBL4850801 0.83 ELANE (0.66) ELANEHPNNPC1RAB9ARXFP1
SCHEMBL10740589 0.83 F7 (0.60) ELANEHPNNPC1RAB9ARXFP1
SCHEMBL17554083 0.82 APEX1 (0.76) ELANEF2C1RMAPTKMT2A
SCHEMBL10781834 0.82 ELANE (0.74) ELANEHPNNPC1RAB9ARXFP1
SCHEMBL29382161 0.82 ELANE (1.00) ELANENPC1RAB9ARXFP1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5093364-A 5-FLUOROANTHRANILIC FUNGICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-03-03 US disclosed
EP-0360417-A2 Derivatives of 4-fluoroanthranilic acid and their use as fungicides SCHERING AGROCHEMICALS LIMITED (GB) 1990-03-28 EP disclosed