Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 9/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745036 | 1.00 | HMGCR (0.54) | HMGCR | |
| SCHEMBL9745032 | 1.00 | HMGCR (0.54) | HMGCR | |
| SCHEMBL9744513 | 0.90 | HMGCR (0.49) | HMGCR | |
| SCHEMBL9744505 | 0.90 | HMGCR (0.49) | HMGCR | |
| SCHEMBL9744517 | 0.90 | HMGCR (0.49) | HMGCR | |
| SCHEMBL9577594 | 0.83 | HMGCR (0.50) | HMGCR | |
| SCHEMBL9577592 | 0.83 | HMGCR (0.50) | HMGCR | |
| SCHEMBL9845323 | 0.83 | HMGCR (0.55) | HMGCR | |
| SCHEMBL9845321 | 0.83 | HMGCR (0.55) | HMGCR | |
| SCHEMBL10408903 | 0.82 | HMGCR (0.54) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114964-A | Aryl-substituted benzocycloalkyl-derived anti-atherosclerotic agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1992-05-19 | — | — | US | claimed |
| US-5114964-A | Aryl-substituted benzocycloalkyl-derived anti-atherosclerotic agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1992-05-19 | — | — | US | disclosed |