Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746155 | 1.00 | RARB (0.56) | RARBNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9745033 | 1.00 | RARB (0.56) | RARBNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9745265 | 1.00 | RARB (0.56) | RARBNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9745673 | 1.00 | RARB (0.56) | RARBNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9329245 | 0.89 | NPC1 (0.62) | RARBNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9513363 | 0.89 | NPC1 (0.62) | RARBNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9733624 | 0.87 | RARB (0.74) | RARBNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7863588 | 0.87 | GAA (0.59) | RARBNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL7863577 | 0.87 | GAA (0.59) | RARBNPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL8532765 | 0.87 | RARB (0.74) | RARBNPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110496-A | LIQUID CRYSTAL COMPOUND | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0445037-A2 | Liquid crystal compound | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1991-09-04 | — | — | EP | disclosed |