Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | RARA | P10276 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 7/20 | 0.49 |
| ▸ | THRB | P10828 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746639 | 1.00 | RARB (0.77) | RARBSMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL9323779 | 1.00 | RARB (0.77) | RARBSMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL9746425 | 1.00 | RARB (0.77) | RARBSMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL7767493 | 1.00 | RARB (0.77) | RARBSMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL6024538 | 1.00 | RARB (0.77) | RARBSMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL11611675 | 0.89 | MAPT (0.65) | RARBSMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL11612451 | 0.89 | MAPT (0.65) | RARBSMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL9745034 | 0.89 | MAPT (0.65) | RARBSMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL9745010 | 0.89 | MAPT (0.65) | RARBSMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL9695388 | 0.88 | RARB (0.58) | RARBSMN1; SMN2MAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110496-A | LIQUID CRYSTAL COMPOUND | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0445037-A2 | Liquid crystal compound | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1991-09-04 | — | — | EP | disclosed |