Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14886259 | 0.89 | — | — | |
| SCHEMBL12503209 | 0.89 | — | — | |
| SCHEMBL22203880 | 0.89 | — | — | |
| SCHEMBL10126105 | 0.87 | — | — | |
| SCHEMBL10031747 | 0.87 | — | — | |
| SCHEMBL12681405 | 0.87 | — | — | |
| SCHEMBL13363499 | 0.87 | — | — | |
| SCHEMBL18456741 | 0.85 | METAP1 (0.55) | METAP1SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL26175812 | 0.85 | METAP1 (0.55) | METAP1SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL27494202 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110191876-A | FORMULATIONS FOR ADMINISTRATION OF EFLORNITHINE | 奥巴斯治疗股份有限公司 | 2019-08-30 | — | — | CN | disclosed |
| US-5171754-A | Use of oxidized polyamines, especially NN'-bis-(3-propionaldehyde)-1-4-diaminobutane (spermine dialdehyde) as immunosuppressive agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |