⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224929 | 0.65 | — | — | |
| SCHEMBL1104797 | 0.62 | — | — | |
| SCHEMBL17406617 | 0.58 | — | — | |
| SCHEMBL411789 | 0.56 | — | — | |
| SCHEMBL976777 | 0.56 | — | — | |
| SCHEMBL7894365 | 0.55 | KDM4E (0.33) | — | |
| SCHEMBL746705 | 0.53 | — | — | |
| SCHEMBL14974556 | 0.53 | — | — | |
| SCHEMBL1062021 | 0.53 | — | — | |
| SCHEMBL3785780 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3134087-B1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | PFIZER (US) | 2020-03-18 | — | — | EP | claimed |
| EP-3137469-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | PFIZER (US) | 2019-10-09 | — | — | EP | claimed |
| EP-3134405-B1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | PFIZER (US) | 2019-08-28 | — | — | EP | claimed |
| US-10077272-B2 | Heteroaromatic compounds and their use as dopamine D1 ligands | PFIZER INC. (US) | 2018-09-18 | — | — | US | claimed |
| US-20180200253-A1 | Heteroaromatic Compounds and their Use as Dopamine D1 Ligands | PFIZER INC. (US) | 2018-07-19 | — | — | US | claimed |
| US-20180072750-A1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | PFIZER INC. (US) | 2018-03-15 | — | — | US | claimed |
| US-9868744-B2 | Heteroaromatic compounds and their use as dopamine D1 ligands | PFIZER INC. (US) | 2018-01-16 | — | — | US | claimed |
| US-9856263-B2 | Heteroaromatic compounds and their use as dopamine D1 ligands | PFIZER INC. (US) | 2018-01-02 | — | — | US | claimed |
| US-9850232-B2 | Heteroaromatic compounds and their use as dopamine D1 ligands | PFIZER INC. (US) | 2017-12-26 | — | — | US | claimed |
| EP-2917216-B1 | HETEROAROMATIC COMPOUNDS AS DOPAMINE D1 LIGANDS | PFIZER (US) | 2017-10-18 | — | — | EP | claimed |
| WO-2015162516-A1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | PFIZER INC. (US) | 2015-10-29 | — | — | WO | claimed |
| US-20150291625-A1 | Heteroaromatic Compounds and their Use as Dopamine D1 Ligands | PFIZER (US) | 2015-10-15 | — | — | US | claimed |
| EP-2917219-A1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | Pfizer Inc. (US) | 2015-09-16 | — | — | EP | claimed |
| EP-2917216-A1 | HETEROAROMATIC COMPOUNDS AS DOPAMINE D1 LIGANDS | Pfizer Inc. (US) | 2015-09-16 | — | — | EP | claimed |
| US-9133190-B2 | Heteroaromatic compounds and their use as dopamine D1 ligands | PFIZER INC. (US) | 2015-09-15 | — | — | US | claimed |
| US-20140336176-A1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | PFIZER INC. (US) | 2014-11-13 | — | — | US | claimed |
| US-8822494-B2 | Heteroaromatic compounds and their use as dopamine D1 ligands | PFIZER INC. (US) | 2014-09-02 | — | — | US | claimed |
| WO-2014072881-A1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | PFIZER INC. (US) | 2014-05-15 | — | — | WO | claimed |
| WO-2014072882-A1 | HETEROAROMATIC COMPOUNDS AS DOPAMINE D1 LIGANDS | PFIZER INC. (US) | 2014-05-15 | — | — | WO | claimed |
| US-20140128374-A1 | HETEROAROMATIC COMPOUNDS AND THEIR USE AS DOPAMINE D1 LIGANDS | PFIZER INC (US) | 2014-05-08 | — | — | US | claimed |