Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14958316 | 0.95 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19POLBMEN1 | |
| SCHEMBL14894872 | 0.93 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19POLBMEN1 | |
| SCHEMBL28292535 | 0.87 | POLB (0.51) | CYP1A2CYP2C9CYP2C19POLBMEN1 | |
| SCHEMBL15404492 | 0.83 | POLB (0.54) | CYP1A2CYP2C9CYP2C19POLBMEN1 | |
| SCHEMBL6182656 | 0.81 | POLB (0.53) | CYP1A2CYP2C9CYP2C19POLBMEN1 | |
| SCHEMBL9364060 | 0.80 | POLB (0.48) | CYP1A2CYP2C9CYP2C19POLBMEN1 | |
| SCHEMBL31148931 | 0.80 | POLB (0.48) | CYP1A2CYP2C9CYP2C19POLBMEN1 | |
| SCHEMBL28193046 | 0.77 | POLB (0.46) | CYP1A2CYP2C9CYP2C19POLBMEN1 | |
| SCHEMBL7470086 | 0.76 | POLB (0.44) | CYP1A2CYP2C9CYP2C19POLBMEN1 | |
| SCHEMBL29028956 | 0.76 | POLB (0.44) | CYP1A2CYP2C9CYP2C19POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110869-A | Block polymerization, endcapping, coupling, chain extension | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-05 | — | — | US | disclosed |