SCHEMBL9745602

SCHEMBL9745602

CCCCC[SiH](C)CCCl

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
ALDH1A1 P00352 1/20 0.46
TDP1 Q9NUW8 1/20 0.43
THRB P10828 1/20 0.35
PLA2G1B P04054 1/20 0.30
HSP90AA1 P07900 1/20 0.30
RAD52 P43351 1/20 0.30
ATG4B Q9Y4P1 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8639212 0.86 TSHR (0.47) TSHRALDH1A1THRBLMNA
SCHEMBL7458807 0.83 TSHR (0.53) TSHRALDH1A1THRBLMNA
SCHEMBL10716954 0.83 TSHR (0.53) TSHRALDH1A1THRBLMNA
SCHEMBL10842394 0.83 TSHR (0.53) TSHRALDH1A1THRBLMNA
SCHEMBL28427180 0.83 TSHR (0.53) TSHRALDH1A1THRBLMNA
SCHEMBL8992346 0.83 TSHR (0.53) TSHRALDH1A1THRBLMNA
SCHEMBL6246201 0.83 TSHR (0.53) TSHRALDH1A1THRBLMNA
SCHEMBL1557285 0.83 TSHR (0.53) TSHRALDH1A1THRBLMNA
SCHEMBL10842205 0.83 TSHR (0.53) TSHRALDH1A1THRBLMNA
SCHEMBL16209969 0.83 TSHR (0.53) TSHRALDH1A1THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed