Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745733 | 1.00 | SPHK1 (0.42) | SPHK1BCHECYP2C9ALDH1A1LMNA | |
| SCHEMBL9743888 | 0.97 | SPHK1 (0.47) | SPHK1BCHECYP2C9ALDH1A1LMNA | |
| SCHEMBL9743880 | 0.97 | SPHK1 (0.47) | SPHK1BCHECYP2C9ALDH1A1LMNA | |
| SCHEMBL9742636 | 0.95 | SPHK1 (0.49) | SPHK1BCHECYP2C9ALDH1A1LMNA | |
| SCHEMBL9743825 | 0.95 | SPHK1 (0.49) | SPHK1BCHECYP2C9ALDH1A1LMNA | |
| SCHEMBL9742629 | 0.95 | SPHK1 (0.49) | SPHK1BCHECYP2C9ALDH1A1LMNA | |
| SCHEMBL9742664 | 0.95 | SPHK1 (0.49) | SPHK1BCHECYP2C9ALDH1A1LMNA | |
| SCHEMBL9743836 | 0.95 | SPHK1 (0.49) | SPHK1BCHECYP2C9ALDH1A1LMNA | |
| SCHEMBL9742655 | 0.95 | SPHK1 (0.49) | SPHK1BCHECYP2C9ALDH1A1LMNA | |
| SCHEMBL9744015 | 0.95 | SPHK1 (0.42) | SPHK1BCHECYP2C9SPHK2ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084204-A | Naphthylacetylenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-01-28 | — | — | US | disclosed |